Sunday, February 02, 2020

Oh When Will They Ever Learn?

Back in the forties through the seventies women who had a history of miscarriages were given DES.
Experts Say Progesterone Could Prevent 8,450 Miscarriages a Year
SciTechDaily
By University Of Birmingham
January 30, 2020

Researchers at the University of Birmingham and Tommy’s National Centre for Miscarriage Research say giving progesterone to women with early pregnancy bleeding and a history of miscarriage could lead to 8,450 more babies being born each year.

The team have published two new studies evidencing both the scientific and economic advantages of giving a course of self-administered twice daily progesterone pessaries to women from when they first present with early pregnancy bleeding up until 16 weeks of pregnancy to prevent miscarriage.

Progesterone is a hormone that is naturally secreted by the ovaries and placenta in early pregnancy and is vital to the attainment and maintenance of healthy pregnancies.

Now the experts are calling for progesterone to be offered as standard in the NHS for women with early pregnancy bleeding and a history of miscarriage after their growing body of research has found it is both cost-effective and can increase women’s chances of having a baby.
I have grave concerns over this, how will progesterone the person in 20 or 30 years?

I worry because this is the exactly how the DES (Diethylstilbestrol) a form of female hormones problems started, DES decreased the number of miscarriages or so they believed but it created massive problems for adults.
Diethylstilbestrol (DES) and Cancer

What is the cancer risk of women who were exposed to DES before birth?
The daughters of women who used DES while pregnant—commonly called DES daughters—have about 40 times the risk of developing clear cell adenocarcinoma of the lower genital tract than unexposed women. However, this type of cancer is still rare; approximately 1 in 1,000 DES daughters develops it.

The first DES daughters who were diagnosed with clear cell adenocarcinoma were very young at the time of their diagnoses (2). Subsequent research has shown that the risk of developing this disease remains elevated as women age into their 40s (5).

DES daughters have an increased risk of developing abnormal cells in the cervix and the vagina that are precursors of cancer (dysplasia, cervical intraepithelial neoplasia, and squamous intraepithelial lesions) (6). These abnormal cells resemble cancer cells, but they do not invade nearby healthy tissue and are not cancer. They may develop into cancer, however, if left untreated. Scientists estimated that DES-exposed daughters were 2.2 times more likely to have these abnormal cell changes in the cervix than unexposed women. Approximately 4% of DES daughters developed these conditions because of their exposure (7). It has been recommended that DES daughters have a yearly Pap test and pelvic exam to check for abnormal cells (6).
[…]
What health problems might DES-exposed sons have?

Some studies have found that men whose mothers used DES during pregnancy have an increased risk of testicular abnormalities, including undescended testicles or development of cysts in the epididymis (13). There is also some evidence of increased risks of inflammation or infection of the testicles (13).

Whether DES-exposed sons have increased risks of testicular or prostate cancer is unclear; studies to date have produced mixed results. As the cohort of these men gets older, more data will be available to help answer this question.

Research has shown that men who were exposed to DES through their mothers do not have an increased risk of infertility, even when they have genital abnormalities (13).
Will Progesterone cause the same problems as DES?

And then there is DES and Gender Dysphoia possible link.
Did DES (Diethylstilbestrol) Cause People To Be Transgender?
Was your mom wowed by the DES anti-miscarriage drug commercials? It may have actually caused transgenderism.
Pathos
By Bruce A Robinson
January 25, 2018

[…]
Diethylstilbestrol (DES) was first synthesized in 1938. It was a medication that was first used in treatment of breast cancers.

Starting about 1940, physicians started prescribing DES in the belief that it would reduce miscarriages and other complications during pregnancy.
[…]
DES Action USA is a non-profit membership agency that was organized in 1977 to support “… all individuals exposed to DES, their families and health care providers.” Their web site’s section on DES Sons states:

“Questions have been routinely raised in the DES community regarding the possibility that prenatal DES exposure may be linked to increased rates for homosexuality, transgender and transsexual conditions. Animal studies point in that direction yet, so far, no evidenced-based research in human populations has been able to confirm it.”

An anonymous woman who goes by the pseudonym “DES Daughter” has an impressive Facebook group, personal journal and an extensive list of links to “Diethylstilbestrol DES and Epigenetic Studies” during the interval 1977 to 2017.

The question of a link between DES and the cause(s) of transgender identity won’t be settled until an extensive, peer reviewed study is conducted.

Until then, we have only speculation.

Unfortunately, the people most concerned about this link are the transgender community, which has limited financial resources to fund such a study.
And I cannot help but wonder will progesterone be going down the same path, have they done any studies on the long term effects?

1 comment:

  1. There was a group on Yahoo back in the 90s that asked these questions; it was rebuffed rather harshly by DES-Action, and I believe there were well over 1000 members who were DES-exposed males; a subgroup needed to be formed because well over a third of the members identified as trans.

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